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type i collagen  (Chondrex Inc)


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    Chondrex Inc type i collagen
    Type I Collagen, supplied by Chondrex Inc, used in various techniques. Bioz Stars score: 93/100, based on 31 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+rat+type+i+collagen+antibody/pm41277704-82-14-17?v=Chondrex+Inc
    Average 93 stars, based on 31 article reviews
    type i collagen - by Bioz Stars, 2026-07
    93/100 stars

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    Expression analysis of CXCR4 in RA. ( a ) RT-qPCR assay of CXCR4 mRNA levels in articular RNA extracted from healthy control mice (HC) and CIA and CAIA mice ( n = 16). ( b ) Detection of expression of CXCR4 in joints of CIA and CAIA mice by immunohistochemistry. ( c ) Analysis of CXCR4 expression in RA ( n = 152), OA ( n = 22), and healthy control (HC) joints (n = 28) using human transcriptome sequencing data from the GEO (GSE89408) database. ( d , e ) Analysis of CXCR4 expression by ( d ) RT-qPCR and ( e ) immunohistochemistry in human synovial tissues isolated from RA and OA after joint replacement surgery ( n = 11). ( f ) CXCR4 expression in immune cells. Synovial tissues of the joints of healthy and CAIA arthritic mice were digested into single-cell suspensions by cathepsin, and CXCR4 expression in each immune cell subpopulation was analyzed by flow cytometry. All RT-qPCR results were normalized with GAPDH. Data are expressed as mean ± SEM. ** P <0.01; *** P <0.001

    Journal: EJNMMI Research

    Article Title: CXCR4-targeted PET imaging in rheumatoid arthritis: a novel approach for monitoring disease activity and therapeutic response

    doi: 10.1186/s13550-025-01203-z

    Figure Lengend Snippet: Expression analysis of CXCR4 in RA. ( a ) RT-qPCR assay of CXCR4 mRNA levels in articular RNA extracted from healthy control mice (HC) and CIA and CAIA mice ( n = 16). ( b ) Detection of expression of CXCR4 in joints of CIA and CAIA mice by immunohistochemistry. ( c ) Analysis of CXCR4 expression in RA ( n = 152), OA ( n = 22), and healthy control (HC) joints (n = 28) using human transcriptome sequencing data from the GEO (GSE89408) database. ( d , e ) Analysis of CXCR4 expression by ( d ) RT-qPCR and ( e ) immunohistochemistry in human synovial tissues isolated from RA and OA after joint replacement surgery ( n = 11). ( f ) CXCR4 expression in immune cells. Synovial tissues of the joints of healthy and CAIA arthritic mice were digested into single-cell suspensions by cathepsin, and CXCR4 expression in each immune cell subpopulation was analyzed by flow cytometry. All RT-qPCR results were normalized with GAPDH. Data are expressed as mean ± SEM. ** P <0.01; *** P <0.001

    Article Snippet: Collagen antibody-induced arthritis (CAIA) was induced in DBA/1 mice using the following protocol: on day 0, the mice received an intraperitoneal (i.p.) injection of 4 mg of a 5-clone anti-collagen monoclonal antibody cocktail (Chondrex).

    Techniques: Expressing, Quantitative RT-PCR, Control, Immunohistochemistry, Sequencing, Isolation, Flow Cytometry

    Overall evaluation and quantification of [ 18 F]AIF-NOTA-QHA-04 uptake in arthritic mice. ( a ) PET imaging and immunohistochemistry analysis of CIA and CAIA arthritic mice compared to healthy controls (HC). Red boxes indicate immunohistochemistry site. ( b ) Correlation between [ 18 F]AIF-NOTA-QHA-04 uptake and arthritis score. ( c , d ) PET images of [ 18 F]AIF-NOTA-QHA-04 uptake at different time points after CIA ( c ) and CAIA ( d ) induction in single representative individual mouse

    Journal: EJNMMI Research

    Article Title: CXCR4-targeted PET imaging in rheumatoid arthritis: a novel approach for monitoring disease activity and therapeutic response

    doi: 10.1186/s13550-025-01203-z

    Figure Lengend Snippet: Overall evaluation and quantification of [ 18 F]AIF-NOTA-QHA-04 uptake in arthritic mice. ( a ) PET imaging and immunohistochemistry analysis of CIA and CAIA arthritic mice compared to healthy controls (HC). Red boxes indicate immunohistochemistry site. ( b ) Correlation between [ 18 F]AIF-NOTA-QHA-04 uptake and arthritis score. ( c , d ) PET images of [ 18 F]AIF-NOTA-QHA-04 uptake at different time points after CIA ( c ) and CAIA ( d ) induction in single representative individual mouse

    Article Snippet: Collagen antibody-induced arthritis (CAIA) was induced in DBA/1 mice using the following protocol: on day 0, the mice received an intraperitoneal (i.p.) injection of 4 mg of a 5-clone anti-collagen monoclonal antibody cocktail (Chondrex).

    Techniques: Imaging, Immunohistochemistry